Overview

  • Product nameAnti-PAIP1 antibody
    See all PAIP1 primary antibodies
  • Description
    Rabbit polyclonal to PAIP1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS) of Human PAIP1 (NP_877590).

  • Positive control
    • Human fetal heart cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionActs as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
  • Sequence similaritiesContains 1 MIF4G domain.
  • DomainOnly the PABPC1-interacting motif-1 (PAM1) stimulates translation initiation.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC12360 antibody
    • OTTHUMP00000221601 antibody
    • OTTMUSP00000026880 antibody
    • PABC1 interacting protein 1 antibody
    • PABP interacting protein 1 antibody
    • PABP-interacting protein 1 antibody
    • PAIP 1 antibody
    • PAIP-1 antibody
    • Paip1 antibody
    • PAIP1_HUMAN antibody
    • Poly(A) binding protein interacting protein 1 antibody
    • Poly(A)-binding protein-interacting protein 1 antibody
    • Polyadenylate binding protein interacting protein 1 antibody
    • Polyadenylate-binding protein-interacting protein 1 antibody
    see all

Anti-PAIP1 antibody images

  • Anti-PAIP1 antibody (ab106325) at 0.5 µg/ml + Human fetal heart cell lysate at 10 µg

    Predicted band size : 54 kDa

References for Anti-PAIP1 antibody (ab106325)

ab106325 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106325.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"