Overview

  • Product name
  • Description
    Rabbit polyclonal to PAIP1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant protein fragment, corresponding to a region within amino acids 99-324 of Human PAIP1 (Q9H074).

  • Positive control
    • A431 whole cell lysate.
  • General notes
    Keep as concentrated solution.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126055 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 54 kDa.

Target

  • Function
    Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
  • Sequence similarities
    Contains 1 MIF4G domain.
  • Domain
    Only the PABPC1-interacting motif-1 (PAM1) stimulates translation initiation.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC12360 antibody
    • OTTHUMP00000221601 antibody
    • OTTMUSP00000026880 antibody
    • PABC1 interacting protein 1 antibody
    • PABP interacting protein 1 antibody
    • PABP-interacting protein 1 antibody
    • PAIP 1 antibody
    • PAIP-1 antibody
    • Paip1 antibody
    • PAIP1_HUMAN antibody
    • Poly(A) binding protein interacting protein 1 antibody
    • Poly(A)-binding protein-interacting protein 1 antibody
    • Polyadenylate binding protein interacting protein 1 antibody
    • Polyadenylate-binding protein-interacting protein 1 antibody
    see all

Images

  • Anti-PAIP1 antibody (ab126055) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 54 kDa

References

ab126055 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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