Overview

  • Product nameAnti-PAIP1 antibody
    See all PAIP1 primary antibodies
  • Description
    Mouse monoclonal to PAIP1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 76 - 186 of Human PAIP1 (NP_877590), with a proprietary tag.

  • Positive control
    • HeLa cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • IsotypeIgG3
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 53 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
    • Sequence similaritiesContains 1 MIF4G domain.
    • DomainOnly the PABPC1-interacting motif-1 (PAM1) stimulates translation initiation.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC12360 antibody
      • OTTHUMP00000221601 antibody
      • OTTMUSP00000026880 antibody
      • PABC1 interacting protein 1 antibody
      • PABP interacting protein 1 antibody
      • PABP-interacting protein 1 antibody
      • PAIP 1 antibody
      • PAIP-1 antibody
      • Paip1 antibody
      • PAIP1_HUMAN antibody
      • Poly(A) binding protein interacting protein 1 antibody
      • Poly(A)-binding protein-interacting protein 1 antibody
      • Polyadenylate binding protein interacting protein 1 antibody
      • Polyadenylate-binding protein-interacting protein 1 antibody
      see all

    Anti-PAIP1 antibody images

    • Anti-PAIP1 antibody (ab92859) at 5 µg/ml + immunogen (111 aa fragment with a tag of 26kDa) at 0.2 µg

      Secondary
      Goat anti-Mouse IgG, HRP conjugated at 1/5000 dilution

      Predicted band size : 53 kDa

    References for Anti-PAIP1 antibody (ab92859)

    ab92859 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92859.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"