Anti-PAK1 interacting protein 1 antibody (ab154544)

Overview

  • Product name
    Anti-PAK1 interacting protein 1 antibody
    See all PAK1 interacting protein 1 primary antibodies
  • Description
    Rabbit polyclonal to PAK1 interacting protein 1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 8-226 of Human PAK1 interacting protein 1 (Uniprot ID: Q9NWT1).

  • Positive control
    • 293T, A431, Jurkat and Raji whole cell lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab154544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 44 kDa.

Target

  • Relevance
    PAK1 interacting protein 1 (PAK1IP1) negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N terminal regulatory domain. PAK1IP1 also binds to the N terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.
  • Cellular localization
    Nuclear, nucleolus.
  • Database links
  • Alternative names
    • bA421M1.5 antibody
    • FLJ20624 antibody
    • hPIP 1 antibody
    • hPIP1 antibody
    • MAK 11 antibody
    • MAK11 antibody
    • p21 activated protein kinase interacting protein 1 antibody
    • PAK- AND PLC-INTERACTING PROTEIN 1 antibody
    • PAK/PLC interacting protein 1 antibody
    • PAK1 interacting protein antibody
    • PAK1IP1 antibody
    • PIP 1 antibody
    • PIP1 antibody
    • Putative PAK inhibitor Skb15 antibody
    • RP11 421M1.5 antibody
    • WD repeat containing protein 84 antibody
    • WDR 84 antibody
    • WDR84 antibody
    see all

Images

  • Anti-PAK1 interacting protein 1 antibody (ab154544) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size: 44 kDa



    10% SDS PAGE

References

ab154544 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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