Overview

  • Product nameAnti-PAK1 + PAK2 antibody
  • Description
    Rabbit polyclonal to PAK1 + PAK2
  • Specificityab63673 detects endogenous levels of total PAK1 + PAK2 proteins.
  • Tested applicationsSuitable for: ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human PAK1 + PAK2 around the phosphorylation site of serine 199 (T-K-SP-V-Y).

  • Positive control
    • HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab63673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.

Target

  • RelevanceIn mammals, there are several identified isoforms of p21 Activated Protein Kinases or PAKs: PAK1 is mostly brain specific, while PAK2 is expressed ubiquitously. The family of serine/threonine p21 activated kinases (PAK) are Rho GTPases effectors for cytoskeleton reorganization and nuclear signaling. They are targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities.
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • Alpha PAK antibody
    • Gamma PAK antibody
    • p21 activated kinase 1 antibody
    • p21 activated kinase 2 antibody
    • P65 PAK antibody
    • P68 PAK antibody
    • PAKalpha antibody
    • PAKgamma antibody
    • Serine/threonine protein kinase PAK 1 antibody
    • Serine/threonine protein kinase PAK 2 antibody
    see all

Anti-PAK1 + PAK2 antibody images

  • ab63673 at 1/500 - 1/1000 dilution staining PAK1 + PAK2 in HeLa cells by Immunofluorescence, in the absence or presence of the immunising peptide.

References for Anti-PAK1 + PAK2 antibody (ab63673)

ab63673 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"