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Anti-pan Cytokeratin antibody [C-11, PCK-26, CY-90, KS-1A3, M20, and A53-B/A2] (ab11213)

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This product is covered by the Abpromise guarantee. Our scientific support team are available to answer any questions or queries - fill out an inquiry form for ab11213 for help.

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1 question for ab11213

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Question 1

Friday 03-March-2006

I wonder if this antibody stains normal respiratory epithelia in the rat as it specific for cytokearitins. If "yes", can you provide me the references? I will very appreciate your response.

ANSWER:

  

Thank you for your enquiry and patience. I was able to obtain the following information from the originators of these antibodies:

For ab11213, "this product should recognise cytokeratins 1, 4, 5, 6, 8,10, 13, 18 and 19. Based on literature, respiratory epithelia expressses cytokeratins 5, 6, 7, and 8. Thus I would believe this antibody would prove suitable but I would not have any references available specific for the use of this antibody for rat respiratory epithelia."

For ab8794, "we have tested this antibody on skin, colon, pancreas and several other epithelial tissues. We have not tested in respiratory epithelia in rat, although this antibody has broad species reactivity, reacts with mouse, rat bovine, others not tested."

I haven't been able to obtain any additional information regarding ab961. If I do, I will pass it on to you. This antibody is a combination of 2 clones and recognizes acidic and basic subfamilies of cytokeratins. The cocktail of these two antibodies can be used to detect most human epithelia. The acidic cytokeratins have molecular weights of 56.5, 55, 51, 50, 50, 48 46, 45, and 40 kDa. The basic cytokeratins have molecular weights of 65-67, 64, 59, 58, 56 and 52.

Please contact us again if you have any additional questions.

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