Anti-pan-AKT (phospho T308) antibody (ab38449)

ab38449 has been referenced in 29 publications.

• Li R  et al. Secreted GRP78 activates EGFR-SRC-STAT3 signaling and confers the resistance to sorafeinib in HCC cells. Oncotarget 8:19354-19364 (2017). WB ; Human . PubMed: 28423613
• Li Y  et al. MicroRNA-210 induces endothelial cell apoptosis by directly targeting PDK1 in the setting of atherosclerosis. Cell Mol Biol Lett 22:3 (2017). WB . PubMed: 28536634
• Wang C  et al. Neuroprotective mechanisms of miR-124 activating PI3K/Akt signaling pathway in ischemic stroke. Exp Ther Med 13:3315-3318 (2017). WB . PubMed: 28587406
• Deng YP  et al. Human bocavirus induces apoptosis and autophagy in human bronchial epithelial cells. Exp Ther Med 14:753-758 (2017). PubMed: 28672995
• Yu J  et al. miR-340 Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cell Line SGC-7901, Possibly via the AKT Pathway. Med Sci Monit 23:71-77 (2017). PubMed: 28057912
• Zhang D  et al. Fibulin-4 promotes osteosarcoma invasion and metastasis by inducing epithelial to mesenchymal transition via the PI3K/Akt/mTOR pathway. Int J Oncol 50:1513-1530 (2017). WB ; Human . PubMed: 28339091
• Lv B  et al. Activated Microglia Induce Bone Marrow Mesenchymal Stem Cells to Produce Glial Cell-Derived Neurotrophic Factor and Protect Neurons Against Oxygen-Glucose Deprivation Injury. Front Cell Neurosci 10:283 (2016). PubMed: 28018176
• Pang X  et al. Role of miR-145 in chronic constriction injury in rats. Exp Ther Med 12:4121-4127 (2016). PubMed: 28105140
• Juvekar A  et al. Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion. Proc Natl Acad Sci U S A 113:E4338-47 (2016). WB, ICC/IF ; Mouse . PubMed: 27402769
• Tu M  et al. MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes. Sci Rep 6:25032 (2016). WB ; Human . PubMed: 27126955
• Lu H  et al. Transient hypoxia reprograms differentiating adipocytes for enhanced insulin sensitivity and triglyceride accumulation. Int J Obes (Lond) 40:121-8 (2016). Mouse . PubMed: 26219415
• Qin G  et al. Melittin inhibits tumor angiogenesis modulated by endothelial progenitor cells associated with the SDF-1a/CXCR4 signaling pathway in a UMR-106 osteosarcoma xenograft mouse model. Mol Med Rep 14:57-68 (2016). WB . PubMed: 27177128
• Yang R  et al. Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling. Mol Med Rep 13:4175-82 (2016). WB ; Human . PubMed: 27035679
• Li T  et al. Wen-Xin Decoction ameliorates vascular endothelium dysfunction via the PI3K/AKT/eNOS pathway in experimental atherosclerosis in rats. BMC Complement Altern Med 16:27 (2016). Rat . PubMed: 26803585
• Li XJ  et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-?B signaling pathways in osteoprotegerin knockout mice. Int J Mol Med N/A:N/A (2016). WB ; Mouse . PubMed: 27840967
• Yang Z  et al. Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway. Oncotarget 6:31916-26 (2015). IHC-P ; Human . PubMed: 26376616
• Gu YJ  et al. GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS axis in hepatocellular carcinoma. Oncotarget 6:33658-74 (2015). WB . PubMed: 26378040
• Kaczmarek MZ  et al. Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells. Leuk Res 38:377-82 (2014). PubMed: 24461365
• Nteeba J  et al. Impact of obesity on ovotoxicity induced by 7,12-dimethylbenz[a]anthracene in mice. Biol Reprod 90:68 (2014). WB ; Mouse . PubMed: 24501177
• Agbemenyah HY  et al. Insulin growth factor binding protein 7 is a novel target to treat dementia. Neurobiol Dis N/A:N/A (2013). WB ; Mouse, Human . PubMed: 24075854
• Choudhary S  et al. Macrophage migratory inhibitory factor promotes bladder cancer progression via increasing proliferation and angiogenesis. Carcinogenesis 34:2891-9 (2013). WB ; Mouse . PubMed: 23825153
• Fleming GF  et al. Phase II trial of temsirolimus in patients with metastatic breast cancer. Breast Cancer Res Treat 136:355-63 (2012). PubMed: 22245973
• Hafner C  et al. Activation of the PI3K/AKT pathway in Merkel cell carcinoma. PLoS One 7:e31255 (2012). IHC-P ; Human . PubMed: 22363598
• Nickkho-Amiry M  et al. Peroxisome proliferator-activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma. Mol Cancer Res 10:441-53 (2012). WB ; Human . PubMed: 22205725
• He Q  et al. Regulation of HIF-1{alpha} activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia. Am J Physiol Endocrinol Metab 300:E877-85 (2011). PubMed: 21343542
• Manetti M  et al. Overexpression of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, leads to insufficient angiogenesis in patients with systemic sclerosis. Circ Res 109:e14-26 (2011). Human . PubMed: 21636803
• Liang R  et al. Post-transcriptional regulation of IGF1R by key microRNAs in long-lived mutant mice. Aging Cell 10:1080-8 (2011). PubMed: 21967153
• Hartz AM  et al. Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 down-regulates blood-brain barrier breast cancer resistance protein. J Pharmacol Exp Ther 334:467-76 (2010). WB ; Rat . PubMed: 20460386
• Wagner M  et al. Selective expansion of the {beta}-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. Am J Physiol Gastrointest Liver Physiol : (2008). PubMed: 18372394