Anti-pan Endothelin antibody [3G10] (ab20860)

Overview

  • Product nameAnti-pan Endothelin antibody [3G10]
  • Description
    Rat monoclonal [3G10] to pan Endothelin
  • SpecificityRecognizes C-terminal region of all endothelins (amino acid residues 15-21) when used as a capture antibody in IRMA assays. Does not cross-react with "big" endothelin.
  • Tested applicationsSuitable for: IHC-Fr, IRMAmore details
    Unsuitable for: IHC-P
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human) conjugated to BSA.

Properties

Applications

Our Abpromise guarantee covers the use of ab20860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent dilution.
IRMA Use at an assay dependent dilution.
  • Application notesIs unsuitable for IHC-P.
  • Target

    • RelevanceEndothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21 amino acid peptides exists in at least three isoforms; ET1, ET2, and ET3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • EDN1 antibody
      • EDN2 antibody
      • EDN3 antibody
      • Endothelin 1 antibody
      • Endothelin 2 antibody
      • Endothelin 3 antibody
      • ET1 antibody
      • ET2 antibody
      • ET3 antibody
      • PPET1 antibody
      • PPET2 antibody
      • PPET3 antibody
      • Preproendothelin 1 antibody
      • Preproendothelin 2 antibody
      • Preproendothelin 3 antibody
      see all

    References for Anti-pan Endothelin antibody [3G10] (ab20860)

    ab20860 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"