Overview

  • Product name
  • Description
    Rabbit polyclonal to Pan3
  • Tested applications
    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 147 and 460 of Human Pan3

  • Positive control
    • H1299, HeLa, HepG2 and Molt4 whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab96325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 82 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function
    Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity.
  • Sequence similarities
    Belongs to the protein kinase superfamily.
    Contains 1 protein kinase domain.
  • Domain
    The protein kinase domain is predicted to be catalytically inactive.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • hPan3 antibody
    • PAB dependent poly(A) specific ribonuclease subunit 3 antibody
    • PAB-dependent poly(A)-specific ribonuclease subunit 3 antibody
    • PAB1P dependent poly(A) nuclease antibody
    • PABP dependent poly(A) nuclease 3 antibody
    • PABP1 dependent poly A specific ribonuclease subunit PAN3 antibody
    • Pan 3 antibody
    • PAN deadenylation complex subunit 3 antibody
    • PAN3 antibody
    • PAN3 poly(A) specific ribonuclease subunit antibody
    • PAN3 poly(A) specific ribonuclease subunit homolog antibody
    • PAN3 polyA specific ribonuclease subunit homolog antibody
    • PAN3_HUMAN antibody
    see all

Images

  • All lanes : Anti-Pan3 antibody (ab96325) at 1/1000 dilution

    Lane 1 : H1299 cell lysate
    Lane 2 : HeLa cell lysate
    Lane 3 : HepG2 cell lysate
    Lane 4 : Molt-4 cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 82 kDa
  • Immunofluorescent analysis of methanol-fixed HeLa cells labeling Pan3 with ab189413 at 1/200 dilution. The lower image is costained with Hoechst 33342.

  • Immunohistochemical analysis of paraffin embedded Human Ca922 xenograft labeling PAN3 with ab96325 at 1/500.

References

ab96325 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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