Overview

  • Product name
    Pancuronium dibromide
  • Description
    Competitive nicotinic acetylcholine receptor (nAChR) antagonist
  • Biological description
    Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine (ab120469) from nAChRs (IC50 = 5.5 nM). Neuromuscular blocker and muscle relaxant.

Properties

Associated products

References

This product has been referenced in:
  • Cembala TM  et al. Allosteric interaction of the neuromuscular blockers vecuronium and pancuronium with recombinant human muscarinic M2 receptors. Eur J Pharmacol 569:37-40 (2007). Read more (PubMed: 17588565) »
  • Löwenick CV  et al. Open channel and competitive block of nicotinic receptors by pancuronium and atracurium. Eur J Pharmacol 413:31-5 (2001). Read more (PubMed: 11173060) »
  • Wenningmann I & Dilger JP The kinetics of inhibition of nicotinic acetylcholine receptors by (+)-tubocurarine and pancuronium. Mol Pharmacol 60:790-6 (2001). Read more (PubMed: 11562442) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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