Overview

  • Product name
  • Description
    Rabbit polyclonal to PANK1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Zebrafish
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 207-483 of Human PANK1.

  • Positive control
    • 293T, A431, H1299, HeLa S3, HepG2, Molt-4, Raji cells, NCIN87 xenograft

Properties

Applications

Our Abpromise guarantee covers the use of ab96173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 64 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Plays a role in the physiological regulation of the intracellular CoA concentration.
  • Tissue specificity
    Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
  • Pathway
    Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
  • Sequence similarities
    Belongs to the type II pantothenate kinase family.
  • Domain
    The N-terminal extension, present in isoform 1 may be the regulatory domain.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • coaA antibody
    • hPanK antibody
    • hPanK1 antibody
    • PANK antibody
    • PANK1 antibody
    • PANK1_HUMAN antibody
    • PANK1a antibody
    • PANK1b antibody
    • PanK1beta antibody
    • Pantothenate kinase 1 antibody
    • Pantothenate kinase antibody
    • Pantothenic acid kinase 1 antibody
    see all

Images

  • Anti-PANK1 antibody (ab96173) at 1/5000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 64 kDa
  • Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using ab96173 at 1/500 dilution.

References

ab96173 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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