Overview

  • Product name
    Anti-PAOX antibody
  • Description
    Rabbit polyclonal to PAOX
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide designed within residues: EVLLCLTQVL RRVTGNPRLP APKSVLRSRW HSAPYTRGSY SYVAVGSTGG, corresponding to C terminal amino acids 398-447 of Human PAOX (AAS64381.1)

  • Positive control
    • Fetal muscle lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab84951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Relevance
    PAOX is a flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. It can also oxidize N(1)-acetylspermidine to putrescine. It does not oxidize spermidine. PAOX plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. There are eleven named isoforms.
  • Cellular localization
    Peroxisome. Cytoplasm.
  • Database links
  • Alternative names
    • DKFZp434J245 antibody
    • MGC45464 antibody
    • PAO antibody
    • Peroxisomal N(1) acetyl spermine/spermidine oxidase antibody
    • Peroxisomal N1 acetyl spermine/spermidine oxidase antibody
    • Polyamine oxidase (exo N4 amino) antibody
    • Polyamine oxidase antibody
    • RP11 122K13.11 antibody
    see all

Images

  • Anti-PAOX antibody (ab84951) at 1 µg/ml + Human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa

References

ab84951 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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