Anti-Papillary renal cell carcinoma antibody (ab114998)

Overview

  • Product name
    Anti-Papillary renal cell carcinoma antibody
    See all Papillary renal cell carcinoma primary antibodies
  • Description
    Rabbit polyclonal to Papillary renal cell carcinoma
  • Tested applications
    Suitable for: IP, IHC-Pmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 125-175 of Human Papillary renal cell carcinoma (NP_005964.3).

  • Positive control
    • Hela whole cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab114998 was affinity purified using an epitope specific to Papillary renal cell carcinomaimmobilized on solid support.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab114998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      May regulate cell cycle progression through interaction with MAD2L2.
    • Tissue specificity
      Ubiquitous in fetal and adult tissues.
    • Involvement in disease
      Note=A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Papillary renal cell carcinoma (Translocation associated), isoform CRA_b antibody
      • Papillary renal cell carcinoma translocation-associated gene protein antibody
      • PRCC antibody
      • PRCC_HUMAN antibody
      • Proline rich protein PRCC antibody
      • Proline-rich protein PRCC antibody
      • RCCP1 antibody
      • TPRC antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling Papillary renal cell carcinoma with ab114998 at 1/1000 (1µg/ml). Detection: DAB.
    • Immunoprecipitation : 1 mg of Hela whole cell lysate immunoprecipitated using ab114998 at 3 µg/mg lysate; 20% of immunoprecipitate loaded per lane

      Western Blot: Anti-Papillary renal cell carcinoma antibody at 1 µg/ml

      developed using the ECL technique

      Exposure time : 10 seconds

      Predicted band size : 52 kDa

    References

    ab114998 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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