Anti-Papillary renal cell carcinoma antibody (ab86602)

Overview

  • Product name
    Anti-Papillary renal cell carcinoma antibody
    See all Papillary renal cell carcinoma primary antibodies
  • Description
    Rabbit polyclonal to Papillary renal cell carcinoma
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between residues 425 and 475 of human Papillary renal cell carcinoma (NP_005964.3)

  • Positive control
    • HeLa, 293T and NIH3T3 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab86602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).
IP Use at 2-5 µg/mg of lysate.

Target

  • Function
    May regulate cell cycle progression through interaction with MAD2L2.
  • Tissue specificity
    Ubiquitous in fetal and adult tissues.
  • Involvement in disease
    Note=A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Papillary renal cell carcinoma (Translocation associated), isoform CRA_b antibody
    • Papillary renal cell carcinoma translocation-associated gene protein antibody
    • PRCC antibody
    • PRCC_HUMAN antibody
    • Proline rich protein PRCC antibody
    • Proline-rich protein PRCC antibody
    • RCCP1 antibody
    • TPRC antibody
    see all

Images

  • All lanes : Anti-Papillary renal cell carcinoma antibody (ab86602) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg
    Lane 4 : 293T whole cell lysate at 50 µg
    Lane 5 : NIH3T3 whole cell lysate at 50 µg


    Predicted band size : 52 kDa
    Observed band size : 52 kDa


    Exposure time : 3 minutes
  • Detection of Papillary renal cell carcinoma by Western Blot of Immunprecipitate.
    ab86602 at 0.4µg/ml staining Papillary renal cell carcinoma in HeLa whole cell lysate immunoprecipitated using ab86602 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 10 seconds.

References

ab86602 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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