Overview

  • Product nameAnti-PAPOLB antibody
    See all PAPOLB primary antibodies
  • Description
    Rabbit polyclonal to PAPOLB
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 432-481 (EEFRTMWVIG LGLKKPDNSE ILSIDLTYDI QSFTDTVYRQ AVNSKMFEMG) of Human PAPOLB (NP_064529; TrEMBL ID: A4D1Z6).

  • Positive control
    • COLO205 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab94691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 72 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceThe function of this protein remains unknown. This gene is a member of the myotubularin family and encodes a putative tyrosine phosphatase. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene, but the protein products of some of these variants are likely not viable, as they are nonsense-mediated mRNA decay (NMD) candidates.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • PAP-beta antibody
    • PAPT antibody
    • poly(A) polymerase beta (testis specific) antibody
    • poly(A) polymerase beta antibody
    • polynucleotide adenylyltransferase beta antibody
    • TPAP antibody
    see all

Anti-PAPOLB antibody images

  • Anti-PAPOLB antibody (ab94691) at 1 µg/ml (in 5% skim milk / PBS buffer) + COLO205 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 72 kDa

References for Anti-PAPOLB antibody (ab94691)

ab94691 has not yet been referenced specifically in any publications.

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