• Product nameAnti-PAPP A antibody [10A5]
    See all PAPP A primary antibodies
  • Description
    Mouse monoclonal [10A5] to PAPP A
  • Tested applicationsSuitable for: ELISA, WB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human PAPPA antigen.

  • General notesConcentration varies from lot to lot and can be provided on request.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein A purified
  • Purification notesPurified by chromatography on protein A sepharose. Purity tested by electrophoresis.
  • ClonalityMonoclonal
  • Clone number10A5
  • MyelomaSp2/0
  • IsotypeIgG2a
  • Research areas


Our Abpromise guarantee covers the use of ab10193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 500 kDa.
Sandwich ELISA Use at an assay dependent dilution.


  • FunctionMetalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
  • Tissue specificityHigh levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts.
  • Sequence similaritiesBelongs to the peptidase M43B family.
    Contains 5 Sushi (CCP/SCR) domains.
  • Developmental stagePresent in serum and placenta during pregnancy; levels increase throughout pregnancy.
  • Post-translational
    There appear to be no free sulfhydryl groups.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ASBABP2 antibody
    • Aspecific BCL2 ARE binding protein 2 antibody
    • Differentially placenta 1 expressed protein antibody
    • DIPLA1 antibody
    • EC antibody
    • IGF dependent IGFBP 4 protease antibody
    • IGF-dependent IGFBP-4 protease antibody
    • IGFBP 4ase antibody
    • IGFBP-4ase antibody
    • IGFBP4ase antibody
    • Insulin like growth factor dependent IGF binding protein 4 protease antibody
    • Insulin-like growth factor-dependent IGF-binding protein 4 protease antibody
    • PAPA antibody
    • PAPP A antibody
    • PAPP-A antibody
    • PAPP1_HUMAN antibody
    • PAPPA antibody
    • PAPPA1 antibody
    • Pappalysin 1 precursor antibody
    • Pappalysin-1 antibody
    • Pregnancy Associated Plasma Protein A antibody
    • Pregnancy associated plasma protein A pappalysin 1 antibody
    • Pregnancy-associated plasma protein A antibody
    see all

References for Anti-PAPP A antibody [10A5] (ab10193)

ab10193 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab10193.
Please use the links above to contact us or submit feedback about this product.