All structural antigens. Cross-reacts with Parainfluenza type 2 but has shown minimal reactivity with Parainfluenza type 1. Does not react with HEp-2 cells by indirect immunofluorescence.
Some cross reactivity with bovine Parainfluenza-3 and canine Parainfluenza.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
Direct FA staining of target antigens in a permissive tissue culture system.
A working dilution must be determined by the user but a starting range of
1:10 - 1:50 is suggested.
Acetone fixation of the antigen source is recommended prior to staining.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Parainfluenza viruses belong to the genus Paramyxovirus of the family Paramyxoviridae. They are enveloped viruses with a single-strand RNA genome of negative polarity and range in diameter from 150 to 200 nm. Four types of parainfluenza viruses have been identified. Types 1 and 2 are major causes of laryngotracheo-bronchitis (croup), with greatest severity in children ages 2 to 4 years. Type 3 infection can also lead to croup but, most notably, is a major cause of infant bronchiolitis, pneumonia, and hospitalization. Infection from type 3 virus is most severe in infants less than 1 year old. Parainfluenza type 4 has been associated only with mild upper respiratory illness in adults and children.
has not yet been referenced specifically in any publications.
Publishing research using ab20310? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Get resources and offers direct to your inboxSign up