Anti-Parainfluenza Virus type 2 and 3 antibody (HRP) (ab20902)

Overview

  • Product name
    Anti-Parainfluenza Virus type 2 and 3 antibody (HRP)
    See all Parainfluenza Virus type 2 and 3 primary antibodies
  • Description
    Goat polyclonal to Parainfluenza Virus type 2 and 3 (HRP)
  • Conjugation
    HRP
  • Specificity
    ab20902 reacts with Parainfluenza Virus type 2. Minimal reactivity with type 1. Some cross-reactivity with bovine Parainfluenza Virus type 3 (<1:400) and canine Parainfluenza Virus (<1,000). Does not react with HEp 2 cells by indirect immunofluorescence.
  • Tested applications
    Suitable for: ELISA, ICCmore details
  • Species reactivity
    Cross-reacts with type 2. Minimal reactivity with type 1. Some cross-reactivity with bovine parainfluenza-3 and canine parainfluenza. Does not react with HEp-2 cells by indirect immunofluorescence.
  • Immunogen

    Human isolate, type 3

  • General notes
    Note: Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

    Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. The estimated molar HRP:IgG substitution is 2-3.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.002% Thimerosal (merthiolate)
    Constituents: PBS, 10mg/ml BSA
  • Concentration information loading...
  • Purity
    IgG fraction
  • Purification notes
    ab21902 is covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Free enzyme is absent.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/200 - 1/1000.
ICC 1/20 - 1/200.

Target

  • Relevance
    Parainfluenza viruses belong to the genus Paramyxovirus of the family Paramyxoviridae. They are enveloped viruses with a single-strand RNA genome of negative polarity and range in diameter from 150 to 200 nm. Four types of parainfluenza viruses have been identified. Types 1 and 2 are major causes of laryngotracheo-bronchitis (croup), with greatest severity in children ages 2 to 4 years. Type 3 infection can also lead to croup but, most notably, is a major cause of infant bronchiolitis, pneumonia, and hospitalization. Infection from type 3 virus is most severe in infants less than 1 year old. Parainfluenza type 4 has been associated only with mild upper respiratory illness in adults and children.

References

ab20902 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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