Anti-Parathyroid Hormone antibody (ab85730)

Overview

  • Product nameAnti-Parathyroid Hormone antibody
    See all Parathyroid Hormone primary antibodies
  • Description
    Goat polyclonal to Parathyroid Hormone
  • Specificityab85730 recognizes Parathyroid hormone amino acids 1-84, 39-84 and 53-84. Does not recognize Parathyroid hormone amino acids 1-34.
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cat, Dog, Cynomolgus Monkey
  • Immunogen

    Synthetic peptide: EWLRKKLQDV HNFVALGAPL APRDAGSQRP RK, corresponding to C terminal amino acids 53-84 of Human Parathyroid Hormone.

  • Positive control
    • Parathyroid tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 40% Glycerol, PBS, pH 7.2
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab85730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionPTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • Involvement in diseaseDefects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • Sequence similaritiesBelongs to the parathyroid hormone family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

Anti-Parathyroid Hormone antibody images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human parathyroid tissue, staining Parathyroid Hormone with ab85730 at 5 µg/ml.

References for Anti-Parathyroid Hormone antibody (ab85730)

ab85730 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab85730.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"