Anti-Parathyroid Hormone antibody [BGN/1F8] (ab63993)

Overview

  • Product nameAnti-Parathyroid Hormone antibody [BGN/1F8]
    See all Parathyroid Hormone primary antibodies
  • Description
    Mouse monoclonal [BGN/1F8] to Parathyroid Hormone
  • Tested applicationsSuitable for: ELISA, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Dog, Pig, Deer, Orangutan
  • Immunogen

    Synthetic peptide: corresponding to amino acids 1-34 of (human) mature PTH conjugated to a proprietary carrier molecule. Ref: NCBI AAA72730.1

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberBGN/1F8
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab63993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 1 - 10 µg/ml.
IHC-P Use a concentration of 10 µg/ml.
IHC-Fr Use a concentration of 10 µg/ml.

Target

  • FunctionPTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • Involvement in diseaseDefects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • Sequence similaritiesBelongs to the parathyroid hormone family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

References for Anti-Parathyroid Hormone antibody [BGN/1F8] (ab63993)

ab63993 has not yet been referenced specifically in any publications.

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The antibody ab63993 has not been tested in WB, however, based on the SwissProt information the protein is about 13 kDa. To detect such a small protein, you're going to have to use a high percentage gel, like...

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Thank you for contacting Abcam. All the antibodies in our catalogue are research use only (RUO). Please let me know if there is anything else I can do to help.

Abcam has not validated the combination of species/application used in this Abreview.
Application ELISA
Sample Rat Recombinant protein (PTH calbiochem #12585)
Specification PTH calbiochem #12585
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2% · Temperature: 28°C
Type Indirect
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Verified customer

Submitted Sep 08 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"