Recombinant
RabMAb

Anti-Parathyroid Hormone antibody [EPR9939] (ab154792)

Overview

  • Product name
    Anti-Parathyroid Hormone antibody [EPR9939]
    See all Parathyroid Hormone primary antibodies
  • Description
    Rabbit monoclonal [EPR9939] to Parathyroid Hormone
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ELISA, WB, IHC-Pmore details
    Unsuitable for: ICC or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to residues in Human Parathyroid Hormone (UniProt P01270).

  • Positive control
    • Tagged Parathyroid Hormone recombinant protein; Human parathyroid gland carcinoma tissue.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20ºC.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR9939
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab154792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB 1/50000 - 1/200000. Predicted molecular weight: 13 kDa.
IHC-P 1/250 - 1/500.
  • Application notes
    Is unsuitable for ICC or IP.
  • Target

    • Function
      PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
    • Involvement in disease
      Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
    • Sequence similarities
      Belongs to the parathyroid hormone family.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • hPTH antibody
      • Parathormone antibody
      • Parathyrin antibody
      • Parathyroid hormone 1 antibody
      • Parathyroid hormone antibody
      • Prepro PTH antibody
      • Preproparathyroid hormone antibody
      • PTH antibody
      • PTH1 antibody
      • PTH1 receptor antibody
      • PTH1R antibody
      • PTHR antibody
      • PTHR1 antibody
      • PTHY_HUMAN antibody
      see all

    Images

    • Direct ELISA antibody dose-response curve using recombinant anti-Human Parathyroid Hormone antibody (ab154792) against full length human parathyroid hormone protein followed Alkaline Phosphatase conjugated Goat Anti-Rabbit IgG secondary antibody.

      Antigen concentration: 100 ng/ml

      Primary ab concentration: 0-1000 ng/ml

      Secondary ab concentration: 1:200 dilution

    • Immunohistochemical analysis of paraffin-embedded Human parathyroid gland carcinoma tissue labeling Parathyroid Hormone with ab154792 at 1/250 dilution.
    • Anti-Parathyroid Hormone antibody [EPR9939] (ab154792) at 1/50000 dilution + Tagged Parathyroid Hormone recombinant protein at 0.01 µg

      Secondary
      Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 13 kDa

    References

    ab154792 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab154792.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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