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Rabbit monoclonal [EPR9939] to Parathyroid Hormone
IHC-P more details Unsuitable for:
ICC or IP
Recombinant fragment corresponding to residues in Human Parathyroid Hormone (UniProt P01270).
Tagged Parathyroid Hormone recombinant protein; Human parathyroid gland carcinoma tissue.
This product is a recombinant rabbit monoclonal antibody.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
Shipped at 4°C. Store at -20ºC.
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration.
1/50000 - 1/200000. Predicted molecular weight: 13 kDa.
1/250 - 1/500.
Is unsuitable for ICC or IP.
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Involvement in disease
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Belongs to the parathyroid hormone family.
Information by UniProt
ELISA - Anti-Parathyroid Hormone antibody [EPR9939] (ab154792)
Direct ELISA antibody dose-response curve using recombinant anti-Human Parathyroid Hormone antibody (ab154792) against full length human parathyroid hormone protein followed Alkaline Phosphatase conjugated Goat Anti-Rabbit IgG secondary antibody.
Antigen concentration: 100 ng/ml
Primary ab concentration: 0-1000 ng/ml
Secondary ab concentration: 1:200 dilution
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Parathyroid Hormone antibody [EPR9939] (ab154792)
Immunohistochemical analysis of paraffin-embedded Human parathyroid gland carcinoma tissue labeling Parathyroid Hormone with ab154792 at 1/250 dilution.
Western blot - Anti-Parathyroid Hormone antibody [EPR9939] (ab154792)
Anti-Parathyroid Hormone antibody [EPR9939] (ab154792) at 1/50000 dilution + Tagged Parathyroid Hormone recombinant protein at 0.01 µg
Secondary Goat anti-rabbit HRP at 1/2000 dilution Predicted band size: 13 kDa
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"