Anti-Parathyroid Hormone Receptor 1 antibody [3D1.1] (ab33187)

Overview

  • Product nameAnti-Parathyroid Hormone Receptor 1 antibody [3D1.1]
    See all Parathyroid Hormone Receptor 1 primary antibodies
  • Description
    Mouse monoclonal [3D1.1] to Parathyroid Hormone Receptor 1
  • SpecificityThis antibody recognizes Parathyroid Hormone Receptor 1, and the receptor dimer. This antibody does not detect the PTH2 receptor. The clone number has been updated to (3D1.1) the clone number name the same antibody clone.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Cow, Human, Pig
    Predicted to work with: Rat, Rabbit, Dog
  • Immunogen

    Synthetic peptide: RRCDRNGSWE LVPGHNRTWA NYSE, corresponding to amino acids 146-169 of Human Parathyroid Hormone Receptor 1.

  • Positive control
    • WB: RIPA lysates of 3T3L1 pre adipose fibroblasts.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 80mM triethylamine, 30% Glycerol, 200mM Glycine. pH 8.0
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number3D1.1
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab33187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 66 kDa.

Target

  • FunctionReceptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
  • Tissue specificityExpressed in most tissues. Most abundant in kidney, bone and liver.
  • Involvement in diseaseJansen metaphyseal chondrodysplasia
    Chondrodysplasia Blomstrand type
    Enchondromatosis multiple
    Eiken skeletal dysplasia
    Primary failure of tooth eruption
  • Sequence similaritiesBelongs to the G-protein coupled receptor 2 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC138426 antibody
    • MGC138452 antibody
    • Parathyroid hormone 1 receptor antibody
    • Parathyroid hormone/parathyroid hormone related peptide receptor antibody
    • Parathyroid hormone/parathyroid hormone related protein receptor antibody
    • Parathyroid hormone/parathyroid hormone-related peptide receptor antibody
    • PTH receptor antibody
    • PTH/PTHr receptor antibody
    • PTH/PTHrP receptor antibody
    • PTH/PTHrP type I receptor antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTH1R_HUMAN antibody
    • PTHR 1 antibody
    • PTHR antibody
    • PTHR1 antibody
    see all

References for Anti-Parathyroid Hormone Receptor 1 antibody [3D1.1] (ab33187)

ab33187 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry.

I can confirm that any publications that we are aware of will be listed on the datasheet. We have a dedicated team who spend time reviewing the literature to find articles that have used our products. However, in ...

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Abcam has not validated the combination of species/application used in this Abreview.
Application Western blot
Sample Rat Cell lysate - whole cell (Hepatic stellate cells)
Loading amount 40 µg
Specification Hepatic stellate cells
Treatment PDGF or TGF
Gel Running Conditions Reduced Denaturing (13%)
Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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Abcam user community

Verified customer

Submitted Aug 13 2012

DISCOUNT CODE: xxxxxx
Expiration date: 06. September 2012
I am very pleased to hear your customer would like to accept our offer and test ab33187 in rat.
This code will give your customer 1 free primary antibody before the expiration dat...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Cow Cell lysate - whole cell (Knee Cartilage, Chondrocytes)
Loading amount 30 µg
Specification Knee Cartilage, Chondrocytes
Gel Running Conditions Reduced Denaturing
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Abcam user community

Verified customer

Submitted Jan 12 2012

I am very pleased to hear you would like to accept our offer and test ab33187 in cow. This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for cow and include this code in the “Addi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"