Anti-Parathyroid Hormone Receptor 1 antibody [3D1.1] (ab33187)

Overview

  • Product name
    Anti-Parathyroid Hormone Receptor 1 antibody [3D1.1]
    See all Parathyroid Hormone Receptor 1 primary antibodies
  • Description
    Mouse monoclonal [3D1.1] to Parathyroid Hormone Receptor 1
  • Specificity
    This antibody recognizes Parathyroid Hormone Receptor 1, and the receptor dimer. This antibody does not detect the PTH2 receptor. The clone number has been updated to (3D1.1) the clone number name the same antibody clone.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Cow, Human, Pig
    Predicted to work with: Rat, Rabbit, Dog
  • Immunogen

    Synthetic peptide: RRCDRNGSWE LVPGHNRTWA NYSE, corresponding to amino acids 146-169 of Human Parathyroid Hormone Receptor 1.

  • Positive control
    • WB: RIPA lysates of 3T3L1 pre adipose fibroblasts.
  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.05% Sodium Azide
    Constituents: 80mM triethylamine, 30% Glycerol, 200mM Glycine. pH 8.0
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    3D1.1
  • Isotype
    IgG1
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab33187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 66 kDa.

Target

  • Function
    Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
  • Tissue specificity
    Expressed in most tissues. Most abundant in kidney, bone and liver.
  • Involvement in disease
    Jansen metaphyseal chondrodysplasia
    Chondrodysplasia Blomstrand type
    Enchondromatosis multiple
    Eiken skeletal dysplasia
    Primary failure of tooth eruption
  • Sequence similarities
    Belongs to the G-protein coupled receptor 2 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC138426 antibody
    • MGC138452 antibody
    • Parathyroid hormone 1 receptor antibody
    • Parathyroid hormone/parathyroid hormone related peptide receptor antibody
    • Parathyroid hormone/parathyroid hormone related protein receptor antibody
    • Parathyroid hormone/parathyroid hormone-related peptide receptor antibody
    • PTH receptor antibody
    • PTH/PTHr receptor antibody
    • PTH/PTHrP receptor antibody
    • PTH/PTHrP type I receptor antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTH1R_HUMAN antibody
    • PTHR 1 antibody
    • PTHR antibody
    • PTHR1 antibody
    see all

References

ab33187 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your enquiry.

I can confirm that any publications that we are aware of will be listed on the datasheet. We have a dedicated team who spend time reviewing the literature to find articles that have used our products. However, in ...

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Abcam has not validated the combination of species/application used in this Abreview.
Application
Western blot
Sample
Rat Cell lysate - whole cell (Hepatic stellate cells)
Loading amount
40 µg
Specification
Hepatic stellate cells
Treatment
PDGF or TGF
Gel Running Conditions
Reduced Denaturing (13%)
Blocking step
Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

Submitted Aug 13 2012

DISCOUNT CODE: xxxxxx
Expiration date: 06. September 2012
I am very pleased to hear your customer would like to accept our offer and test ab33187 in rat.
This code will give your customer 1 free primary antibody before the expiration dat...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Western blot
Sample
Cow Cell lysate - whole cell (Knee Cartilage, Chondrocytes)
Loading amount
30 µg
Specification
Knee Cartilage, Chondrocytes
Gel Running Conditions
Reduced Denaturing
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Abcam user community

Verified customer

Submitted Jan 12 2012

I am very pleased to hear you would like to accept our offer and test ab33187 in cow. This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for cow and include this code in the “Addi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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