Overview

  • Product nameAnti-PARC antibody
    See all PARC primary antibodies
  • Description
    Mouse monoclonal to PARC
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 918-1026 of Human PARC

Properties

Applications

Our Abpromise guarantee covers the use of ab57032 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCytoplasmic anchor protein in p53-associated protein complex. Regulates the subcellular localization of p53 and subsequent function. Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex. In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity.
    • Tissue specificityUbiquitously expressed in all tissues with highest expression in testis brain and kidney.
    • Sequence similaritiesBelongs to the cullin family.
      Contains 1 DOC domain.
      Contains 1 IBR-type zinc finger.
      Contains 2 RING-type zinc fingers.
    • DomainThe IBR domain is required for interaction with UBCH7 and UBCH8.
    • Post-translational
      modifications
      In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin.
      Neddylated.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • CUL-9 antibody
      • Cul9 antibody
      • CUL9_HUMAN antibody
      • Cullin-9 antibody
      • DKFZp686G1042 antibody
      • DKFZp686P2024 antibody
      • H7AP1 antibody
      • KIAA0708 antibody
      • OTTHUMP00000039816 antibody
      • p53 associated parkin like cytoplasmic protein antibody
      • p53-associated parkin-like cytoplasmic protein antibody
      • PARC antibody
      • parkin-like cytoplasmic p53 binding protein antibody
      • RP3 330M21.2 antibody
      • UbcH 7 associated protein 1 antibody
      • UbcH7 associated protein 1 antibody
      • UbcH7-associated protein 1 antibody
      see all

    Anti-PARC antibody images



    • Predicted band size : 281 kDa
      PARC antibody (ab57032) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    References for Anti-PARC antibody (ab57032)

    ab57032 has not yet been referenced specifically in any publications.

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