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ab15954 has been referenced in 29 publications.

  • Gao H  et al. Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress. Sci Rep 6:34403 (2016). ICC/IF ; Rat . PubMed: 27679973
  • Im E  et al. Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin. Open Biol 6:N/A (2016). WB . PubMed: 27534820
  • Smith GA  et al. Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition. Mol Neurobiol 53:5161-77 (2016). WB, ICC/IF ; Human . PubMed: 26399642
  • Corsetti V  et al. NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease. Hum Mol Genet 24:3058-81 (2015). PubMed: 25687137
  • Seillier M  et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med 7:802-18 (2015). WB . PubMed: 25828351
  • Choubey V  et al. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy 10:1105-19 (2014). IP ; Rat . PubMed: 24879156
  • Zou J  et al. Autophagy inhibitor LRPPRC suppresses mitophagy through interaction with mitophagy initiator Parkin. PLoS One 9:e94903 (2014). WB, ICC/IF ; Human . PubMed: 24722279
  • Yun J  et al. MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin. Elife (Cambridge) 3:e01958 (2014). ICC/IF ; Human . PubMed: 24898855
  • Ivatt RM  et al. Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy. Proc Natl Acad Sci U S A 111:8494-9 (2014). PubMed: 24912190
  • Cummins TD  et al. Metabolic remodeling of white adipose tissue in obesity. Am J Physiol Endocrinol Metab 307:E262-77 (2014). PubMed: 24918202
  • Strappazzon F  et al. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell Death Differ N/A:N/A (2014). PubMed: 25215947
  • Khasnavis S & Pahan K Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neuroimmune Pharmacol 9:569-81 (2014). PubMed: 24946862
  • Kim SJ  et al. Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. PLoS Pathog 9:e1003285 (2013). WB, IP, ICC/IF ; Human . PubMed: 23555273
  • Hoshino A  et al. Cytosolic p53 inhibits Parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart. Nat Commun 4:2308 (2013). PubMed: 23917356
  • Manzanillo PS  et al. The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature 501:512-6 (2013). PubMed: 24005326
  • Zanon A  et al. Profiling of Parkin-binding partners using tandem affinity purification. PLoS One 8:e78648 (2013). IP ; Human . PubMed: 24244333
  • Kim SJ  et al. Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis. PLoS Pathog 9:e1003722 (2013). Human . PubMed: 24339771
  • Chen Y  et al. The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint. Biochim Biophys Acta 1822:573-80 (2012). Human . PubMed: 22200450
  • Miñones-Moyano E  et al. MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. Hum Mol Genet : (2011). PubMed: 21558425
  • Chan NC  et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 20:1726-37 (2011). WB ; Human . PubMed: 21296869
  • Cui M  et al. Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J Biol Chem 285:11740-52 (2010). WB ; Rat . PubMed: 20164189
  • Sriram K  et al. Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes. FASEB J 24:4989-5002 (2010). WB ; Rat . PubMed: 20798247
  • Vives-Bauza C  et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci U S A 107:378-83 (2010). WB, ICC/IF ; Human . PubMed: 19966284
  • Geisler S  et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 12:119-31 (2010). ICC/IF, IP ; Human . PubMed: 20098416
  • Rothfuss O  et al. Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair. Hum Mol Genet 18:3832-50 (2009). WB, ICC/IF, ChIP ; Human . PubMed: 19617636
  • Brody KM  et al. Regional and cellular localisation of Parkin co-regulated gene in developing and adult mouse brain. Brain Res 1201:177-86 (2008). WB, IHC-Fr ; Mouse . PubMed: 18295750
  • Helton TD  et al. Pruning and loss of excitatory synapses by the parkin ubiquitin ligase. Proc Natl Acad Sci U S A 105:19492-7 (2008). ICC/IF ; Rat . PubMed: 19033459
  • Ren Y & Feng J Rotenone selectively kills serotonergic neurons through a microtubule-dependent mechanism. J Neurochem 103:303-11 (2007). PubMed: 17587308
  • Feng J Microtubule: a common target for parkin and Parkinson's disease toxins. Neuroscientist 12:469-76 (2006). PubMed: 17079513


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