Overview

  • Product name
  • Description
    Rabbit polyclonal to PARM-1
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: VPPTTIWTSS PQNTDADTAS PSNGTHNNSV LPVTASAPTS LLPKNISIES REEEITSPGS NWEGTNTDPS PSGFSSTSGG VHLTTTLEEH SSGT, corresponding to amino acids 36-129 of Human PARM-1

  • Positive control
    • Human colon tissue; A431 cells; RT4 and U251 MG lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixed/permeabilized with PFA/Triton X-100
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis.
  • Tissue specificity
    Widely expressed with highest levels in heart, kidney and placenta.
  • Sequence similarities
    Belongs to the PARM family.
  • Post-translational
    modifications
    Highly N-glycosylated and O-glycosylated.
  • Cellular localization
    Cell membrane. Golgi apparatus membrane. Endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • PARM 1 antibody
    • PARM-1 antibody
    • PARM1 antibody
    • PARM1_HUMAN antibody
    • Prostate androgen regulated mucin like protein 1 antibody
    • Prostate androgen-regulated mucin-like protein 1 antibody
    see all

Images

  • ab122452 at 4 µg/ml staining PARM-1 in PFA/Triton X-100 fixed/permeabilized A431 cells by Immunofluorescence (antibody staining is shown in green).

References

ab122452 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab122452.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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