Overview

  • Product name
    Paroxetine hydrochloride
  • Description
    5-HT uptake inhibitor
  • Biological description
    Potent, selective 5-HT (serotonin) uptake inhibitor. Inhibits human and rat 5-HT transporters (Ki values are 0.065 and 0.05 nM, respectively). Antidepressant and anxiolytic in vivo.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Bourin M  et al. Paroxetine: a review. CNS Drug Rev 7:25-47 (2001). Read more (PubMed: 11420571) »
  • Owens MJ  et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther 283:1305-22 (1997). Read more (PubMed: 9400006) »
  • Thomas DR  et al. Biochemical effects of the antidepressant paroxetine, a specific 5-hydroxytryptamine uptake inhibitor. Psychopharmacology (Berl) 93:193-200 (1987). Read more (PubMed: 2962217) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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