Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Widely expressed, mainly in actively dividing tissues. The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low in leukocytes, colon, small intestine, prostate and thymus.
Poly (ADP ribose) polymerase family member 2 antibody
Poly (ADP ribosyl) transferase like 2 antibody
poly (ADP-ribose) polymerase 2 antibody
Poly [ADP ribose] synthetase 2 antibody
Poly [ADP-ribose] polymerase 2 antibody
Poly(ADP ribose) synthetase antibody
Poly[ADP-ribose] synthase 2 antibody
Western blot - Anti-PARP2 [AT29G4] antibody (ab177529)
Lane 1 : Anti-PARP2 antibody [AT29G4] (ab177529) at 1/500 dilution Lane 2 : Anti-PARP2 antibody [AT29G4] (ab177529) at 1/1000 dilution Lane 3 : Anti-PARP2 antibody [AT29G4] (ab177529) at 1/5000 dilution
Lane 1 : HeLa cell lysate Lane 2 : HeLa cell lysate Lane 3 : HeLa cell lysate
Lysates/proteins at 40 µg per lane.
Secondary goat anti-mouse secondary antibody conjugated to
HRP Developed using the ECL technique