Anti-PARP9 antibody - N-terminal (ab170609)

Overview

  • Product name
    Anti-PARP9 antibody - N-terminal
    See all PARP9 primary antibodies
  • Description
    Rabbit polyclonal to PARP9 - N-terminal
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Mouse PARP9 aa 404-434 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q8CAS9

  • Positive control
    • Mouse liver tissue lysate; Human rectum tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab170609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Predicted molecular weight: 97 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Involved in inducing the expression of IFN-gamma-responsive genes.
  • Tissue specificity
    Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells.
  • Involvement in disease
    Note=Overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression in B-cell lymphoma transfectants may promote malignant B-cell migration. May therefore be involved in promoting B-cell migration and dissemination of high-risk DLB-CL tumors.
  • Sequence similarities
    Contains 2 Macro domains.
    Contains 1 PARP catalytic domain.
  • Cellular localization
    Cytoplasm > cytosol. Nucleus. Shuttles between the nucleus and the cytosol. Export to the cytosol depends on the interaction with DTX3L.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADP-ribosyltransferase diphtheria toxin-like 9 antibody
    • ARTD9 antibody
    • AW214463 antibody
    • B aggressive lymphoma protein antibody
    • Bagl antibody
    • BAL antibody
    • BAL1 antibody
    • BC003281 antibody
    • DKFZp666B0810 antibody
    • DKFZp686M15238 antibody
    • EC 2.4.2.30 antibody
    • FLJ26637 antibody
    • FLJ35310 antibody
    • FLJ41418 antibody
    • FLJ43593 antibody
    • MGC:7868 antibody
    • MGC156739 antibody
    • MGC7868 antibody
    • OTTMUSP00000028034 antibody
    • PARP 9 antibody
    • PARP-9 antibody
    • Parp9 antibody
    • PARP9_HUMAN antibody
    • Poly (ADP ribose) polymerase family member 9 antibody
    • Poly [ADP-ribose] polymerase 9 antibody
    • RGD1307534 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human rectum tissue labeling PARP9 with ab170609 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-PARP9 antibody - N-terminal (ab170609) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 97 kDa

References

ab170609 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab170609.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up