Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
Involvement in diseaseA chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6. Leukemia, acute lymphoblastic, 3
Sequence similaritiesContains 1 paired domain.
Developmental stageExpressed at early B-cell differentiation, in the developing CNS and in adult testis.
Paired box gene 5 (B cell lineage specific activator) antibody
Paired box gene 5 antibody
Paired box homeotic gene 5 antibody
Paired box protein Pax 5 antibody
Paired box protein Pax-5 antibody
Paired domain gene 5 antibody
PAX 5 antibody
Transcription factor PAX 5 antibody
Anti-PAX5 antibody [EPR3729] images
Western blot - PAX5 antibody [EPR3729] (ab92512)
All lanes : Anti-PAX5 antibody [EPR3729] (ab92512) at 1/1000 dilution
Lane 1 : Ramos cell lysate Lane 2 : Daudi cell lysate
Lysates/proteins at 10 µg per lane.
Secondary HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size : 42 kDa
References for Anti-PAX5 antibody [EPR3729] (ab92512)
This product has been referenced in:
Deng J et al. Applicability of the methylated CpG sites of paired box 5 (PAX5) promoter for prediction the prognosis of gastric cancer. Oncotarget5:7420-30 (2014).
Read more (PubMed: 25277182) »