The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use a concentration of 0.1 µg/ml. Predicted molecular weight: 19 kDa.
FunctionResponsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells.
Tissue specificityFound in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Sequence similaritiesBelongs to the TspO/BZRP family.
ab104546 at 2.5µg/ml staining PBR in Human colon by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
ab104546 at 2.5µg/ml staining PBR in Human kidney by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Western blot - PBR antibody (ab104546)
Anti-PBR antibody (ab104546) at 0.1 µg/ml + Human Brain lysate at 35 µg/ml developed using the ECL technique
Predicted band size : 19 kDa
References for Anti-PBR antibody (ab104546)
has not yet been referenced specifically in any publications.
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