Validated using a knockout cell line

Anti-PBR antibody [EPR5384] (ab109497)

Publishing research using ab109497? Please let us know so that we can cite the reference in this datasheet.

ab109497 has been referenced in 22 publications.

  • Chaney A  et al. Longitudinal investigation of neuroinflammation and metabolite profiles in the APPswe ×PS1?e9 transgenic mouse model of Alzheimer's disease. J Neurochem 144:318-335 (2018). IHC ; Mouse . PubMed: 29124761
  • Song D  et al. Complement C5a receptor knockout has diminished light-induced microglia/macrophage retinal migration. Mol Vis 23:210-218 (2017). IHC-Fr ; Mouse . PubMed: 28442885
  • Li HD  et al. A translocator protein 18 kDa agonist protects against cerebral ischemia/reperfusion injury. J Neuroinflammation 14:151 (2017). PubMed: 28754131
  • Hescot S  et al. Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches. Oncotarget 8:109924-109940 (2017). PubMed: 29299119
  • Yang J  et al. Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and64CuCl2. Sci Rep 7:8298 (2017). PubMed: 28811616
  • James ML  et al. [18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease. Theranostics 7:1422-1436 (2017). IHC-FrFl ; Mouse . PubMed: 28529627
  • Barron AM  et al. Assessment of neuroinflammation in a mouse model of obesity and ß-amyloidosis using PET. J Neuroinflammation 13:221 (2016). IHC-Fr ; Mouse . PubMed: 27578213
  • Wang H  et al. Global Deletion of TSPO Does Not Affect the Viability and Gene Expression Profile. PLoS One 11:e0167307 (2016). WB, IHC ; Mouse . PubMed: 27907096
  • Zhang S  et al. Tumor mitochondria-targeted photodynamic therapy with a translocator protein (TSPO)-specific photosensitizer. Acta Biomater 28:160-170 (2015). PubMed: 26432436
  • Tóth M  et al. Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking. Brain Struct Funct N/A:N/A (2015). PubMed: 25601153
  • Selvaraj V  et al. Minireview: translocator protein (TSPO) and steroidogenesis: a reappraisal. Mol Endocrinol 29:490-501 (2015). PubMed: 25730708
  • Fan J  et al. Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. Proc Natl Acad Sci U S A 112:7261-6 (2015). PubMed: 26039990
  • Zhao L  et al. Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration. EMBO Mol Med 7:1179-97 (2015). IHC . PubMed: 26139610
  • Banati RB  et al. Positron emission tomography and functional characterization of a complete PBR/TSPO knockout. Nat Commun 5:5452 (2014). WB, IHC ; Mouse . PubMed: 25406832
  • Karlstetter M  et al. Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis. J Neuroinflammation 11:3 (2014). WB, ICC/IF ; Mouse . PubMed: 24397957
  • Wang M  et al. Macroglia-microglia interactions via TSPO signaling regulates microglial activation in the mouse retina. J Neurosci 34:3793-806 (2014). Mouse . PubMed: 24599476
  • Buckman LB  et al. Regulation of S100B in white adipose tissue by obesity in mice. Adipocyte 3:215-20 (2014). ICC/IF ; Human . PubMed: 25068089
  • Tu LN  et al. Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis. J Biol Chem 289:27444-54 (2014). WB, IHC ; Mouse . PubMed: 24936060
  • Gatliff J  et al. TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control. Autophagy 10:2279-96 (2014). PubMed: 25470454
  • Faccenda D  et al. IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling. Cell Death Differ 20:686-97 (2013). WB ; Mouse, Human . PubMed: 23348567
  • Morohaku K  et al. Developmental expression of translocator protein/peripheral benzodiazepine receptor in reproductive tissues. PLoS One 8:e74509 (2013). WB, ICC/IF ; Mouse . PubMed: 24040265
  • Thompson MM  et al. Translocator protein 18 kDa (TSPO) is regulated in white and brown adipose tissue by obesity. PLoS One 8:e79980 (2013). IHC-P ; Mouse . PubMed: 24260329


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