Overview

  • Product nameAnti-PBX2 antibody
    See all PBX2 primary antibodies
  • Description
    Mouse monoclonal to PBX2
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: DMFLGMPGLN GDSYSASQVE SLRHSMGPGG YGDNLGGGQM YSPREMRANG SWQEAVTPSS VTSPTEGPGS VHSDTSN, corresponding to amino acids 354-431 of Human PBX2

Properties

Applications

Our Abpromise guarantee covers the use of ab55498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 46 kDa.
ICC/IF Use a concentration of 10 µg/ml.

Target

  • RelevancePBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family and was identified by its similarity to a homeobox gene involved in t(1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter, binding to the sequence 5'-ATCAATCAA-3'. It forms heterodimers with MEIS1, involved in activation of PF4 transcription, and heterotrimers with MEIS1 and HOXA9. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • G17 antibody
    • Homeobox protein PBX2 antibody
    • HOX12 antibody
    • PBX2MHC antibody
    • pre-B-cell leukemia homeobox 2 antibody
    • pre-B-cell leukemia transcription factor 2 antibody
    • Protein G17 antibody
    see all

Anti-PBX2 antibody images



  • Predicted band size : 46 kDa
    PBX2 antibody (ab55498) at 1ug/lane + HeLa cell lysate at 25ug/lane.
  • ab55498 at 10 ug/ml staining PBX2 in human Hella cells by Immunocytochemistry/ Immunofluorescence.

References for Anti-PBX2 antibody (ab55498)

ab55498 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"