Overview

  • Product nameAnti-PBXIP1 antibody
    See all PBXIP1 primary antibodies
  • Description
    Rabbit polyclonal to PBXIP1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between amino acids 175 and 225 of human PBXIP1 (NP_079033.3).

  • Positive control
    • Breast carcinoma, ovarian carcinoma,anaplastic tyroid carcinoma,pancreatic islet cell tumor,stomach adenocarcinoma,testicular seminoma,stomach adenocarcinoma,prostrate carcinoma,linitis plastica stomach cancer,metastatic lymph node,teratoma

Properties

Applications

Our Abpromise guarantee covers the use of ab84752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevancePBXIP1 is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 also tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
    • Cellular localizationCytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus.
    • Database links
    • Alternative names
      • 4732463H20Rik antibody
      • Hematopoietic PBX interacting protein antibody
      • HPIP antibody
      • MGC38361 antibody
      • Pre B cell leukemia homeobox interacting protein 1 antibody
      • RP11-307C12.2 antibody
      see all

    Anti-PBXIP1 antibody images

    • Detection of mouse HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of mouse teratoma , using ab84752 at a 1/100 dilution.
      Detection: DAB staining.
    • Detection of human HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of human ovarian carcinoma, using ab84752 at a 1/100 dilution.
      Detection: DAB staining.
    • Detection of human HPIP by immunohistochemistry immunofluorescence of human ovarian carcinoma, using ab84752 at 1/100 dilution.
      Detection: red fluorescent Goat anti-Rabbit IgG diluted 1/100.

    References for Anti-PBXIP1 antibody (ab84752)

    ab84752 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"