Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.
Contains 3 KH domains.
Phosphorylated; lowers poly(rC)-binding activity.
Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Detection of PCBP1 by Western Blot of Immunprecipitate.
293T cell lysate immunoprecipitated using ab168378 at 1/10 dilution; HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.