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Rabbit polyclonal to PCCA
Predicted to work with:
Recombinant fragment, corresponding to a region within amino acids 482-716 of Human PCCA (UniProt ID: P05165).
HeLa whole cell lysate; U87 xenograft
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 78% PBS, 20% Glycerol, 1% BSA
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 77 kDa.
1/100 - 1/1000.
Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
Involvement in disease
Defects in PCCA are the cause of propionic acidemia type I (PA-1) [MIM:606054]. PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
Contains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain. Contains 1 biotinyl-binding domain.
Information by UniProt
pccA COMPLEMENTATION GROUP antibody
Western blot - Anti-PCCA antibody (ab154254)
Anti-PCCA antibody (ab154254) at 1/5000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 77 kDa 7.5% SDS PAGE
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PCCA antibody (ab154254)
Immunohistochemical analysis of paraffin-embedded U87 xenograft tissue labeling PCCA with ab154254 at 1/500 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"