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Rabbit polyclonal to PCCB
Predicted to work with:
Mouse, Rat, Cow, Pig, Zebrafish
Recombinant fragment, corresponding to a region within amino acids 167-450 of Human PCCB (NP_000523).
HepG2 cell lysate for WB and Lung Ad Cancer PC14 for IHC-P
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/250.
1/500 - 1/3000. Predicted molecular weight: 58 kDa.
Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
Involvement in disease
Defects in PCCB are the cause of propionic acidemia type II (PA-2) [MIM:606054]. PA-2 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
Belongs to the AccD/PCCB family.
Contains 1 carboxyltransferase domain.
Information by UniProt
PCCase subunit beta antibody
Western blot - Anti-PCCB antibody (ab96729)
Anti-PCCB antibody (ab96729) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 58 kDa 7.5% SDS PAGE
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PCCB antibody (ab96729)
Immunohistochemical analysis of paraffin-embedded Lung Ad Cancer PC14, using ab96729 at 1:100 dilution.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"