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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/250.
1/500 - 1/3000. Predicted molecular weight: 58 kDa.
Pathway Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.
Involvement in disease Defects in PCCB are the cause of propionic acidemia type II (PA-2) [MIM:606054]. PA-2 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
Sequence similarities Belongs to the AccD/PCCB family. Contains 1 carboxyltransferase domain.
Cellular localization Mitochondrion matrix.
Information by UniProt
PCCase subunit beta antibody
Anti-PCCB antibody images
Western blot - PCCB antibody (ab96729)
Anti-PCCB antibody (ab96729) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg Predicted band size : 58 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PCCB antibody (ab96729)
Immunohistochemical analysis of paraffin-embedded Lung Ad Cancer PC14, using ab96729 at 1:100 dilution.
References for Anti-PCCB antibody (ab96729)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"