Anti-PCDH12 antibody (ab82885)

Overview

• Product nameAnti-PCDH12 antibody
  See all PCDH12 primary antibodies
• Description
  Rabbit polyclonal to PCDH12
• Tested applicationsSuitable for: WBmore details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
• Immunogen

  Synthetic peptide corresponding to a region within internal sequence amino acids 612-661 (SSRPFLLTTI VARDADSGAN GEPLYSIRSG NEAHLFILNP HTGQLFVNVT) of human PCDH12 (NP_057664).

  Run BLAST with Run BLAST with
• Positive control
  • MCF7 cell lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 2% Sucrose, PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Neuroscience
  • Cell Adhesion Proteins
  • Membrane Proteins

  • Signal Transduction
  • Cytoskeleton / ECM
  • Cell Adhesion
  • Cadherins

  • Developmental Biology
  • Reproduction
  • Placental development

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
• Positive Controls
  • MCF7 membrane extract lysate (ab29539)

Applications

Target

• FunctionCellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.
• Tissue specificityExpressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen.
• Sequence similaritiesContains 6 cadherin domains.
• Cellular localizationCell membrane. Cell junction.

• Target information above from: UniProt accession Q9NPG4 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 51294 Human
  • Entrez Gene: 116808 Rat
  • Omim: 605622 Human
  • SwissProt: Q9NPG4 Human
  • Unigene: 439474 Human
• Alternative names
  • PCD12_HUMAN antibody
  • Pcdh12 antibody
  • Protocadherin 12 antibody

  • Protocadherin-12 antibody
  • Vascular cadherin 2 antibody
  • Vascular cadherin-2 antibody
  • Vascular endothelial cadherin 2 antibody
  • Vascular endothelial cadherin-2 antibody
  • VE cadherin 2 antibody
  • VE-cad-2 antibody
  • VE-cadherin-2 antibody
  • VECAD2 antibody

  see all