Overview

  • Product nameAnti-PCDH12 antibody
    See all PCDH12 primary antibodies
  • Description
    Rabbit polyclonal to PCDH12
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 612-661 (SSRPFLLTTI VARDADSGAN GEPLYSIRSG NEAHLFILNP HTGQLFVNVT) of human PCDH12 (NP_057664).

  • Positive control
    • MCF7 cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab82885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 129 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.
  • Tissue specificityExpressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen.
  • Sequence similaritiesContains 6 cadherin domains.
  • Cellular localizationCell membrane. Cell junction.
  • Information by UniProt
  • Database links
  • Alternative names
    • PCD12_HUMAN antibody
    • Pcdh12 antibody
    • Protocadherin 12 antibody
    • Protocadherin-12 antibody
    • Vascular cadherin 2 antibody
    • Vascular cadherin-2 antibody
    • Vascular endothelial cadherin 2 antibody
    • Vascular endothelial cadherin-2 antibody
    • VE cadherin 2 antibody
    • VE-cad-2 antibody
    • VE-cadherin-2 antibody
    • VECAD2 antibody
    see all

Anti-PCDH12 antibody images

  • Anti-PCDH12 antibody (ab82885) at 1 µg/ml + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 129 kDa
    Observed band size : 143 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 45 kDa,65 kDa. We are unsure as to the identity of these extra bands.

References for Anti-PCDH12 antibody (ab82885)

ab82885 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82885.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"