Overview

  • Product nameAnti-PCDHGB1 antibody
    See all PCDHGB1 primary antibodies
  • Description
    Mouse polyclonal to PCDHGB1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length PCDHGB1 protein (Human)

  • Positive control
    • PCDHGB1 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab67572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 110 kDa (predicted molecular weight: 100 kDa).

Target

  • RelevanceThe PCDHGB1 gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
  • Cellular localizationCell membrane; Single-pass type I membrane protein.
  • Database links
  • Alternative names
    • MGC119466 antibody
    • MGC119467 antibody
    • MGC119469 antibody
    • PCDH gamma B1 antibody
    • Protocadherin gamma B1 antibody
    • Protocadherin gamma B1 precursor antibody
    • Protocadherin gamma subfamily B 1 antibody
    see all

Anti-PCDHGB1 antibody images

  • All lanes : Anti-PCDHGB1 antibody (ab67572) at 1/500 dilution

    Lane 1 : PCDHGB1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 100 kDa
    Observed band size : 110 kDa (why is the actual band size different from the predicted?)

References for Anti-PCDHGB1 antibody (ab67572)

ab67572 has not yet been referenced specifically in any publications.

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