Overview

  • Product nameAnti-PCOLCE antibody - Carboxyterminal end
    See all PCOLCE primary antibodies
  • Description
    Rabbit polyclonal to PCOLCE - Carboxyterminal end
  • Specificityab39204 recognizes both full sized and cleaved PCOLE1 and does not react with PCOLE2.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human, Pig
  • Immunogen

    Synthetic peptide based on the end of CUB2 and the beginning of the "linker" region of Human PCOLCE. (Peptide available as ab41294.)

Properties

Applications

Our Abpromise guarantee covers the use of ab39204 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 53 kDa (predicted molecular weight: 48 kDa). A recommended starting concentration for Western blots is 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates.

Target

  • FunctionBinds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
    C-terminal processed part of PCPE (CT-PCPE) may have an metalloproteinase inhibitory activity.
  • Sequence similaritiesContains 2 CUB domains.
    Contains 1 NTR domain.
  • Post-translational
    modifications
    C-terminally processed at multiple positions.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • PCOC1_HUMAN antibody
    • Pcolce antibody
    • PCOLE 1 antibody
    • PCOLE1 antibody
    • PCPE antibody
    • PCPE-1 antibody
    • PCPE1 antibody
    • Procollagen C endopeptidase enhancer antibody
    • Procollagen C-endopeptidase enhancer 1 antibody
    • Procollagen C-endopeptidase enhancer antibody
    • Procollagen C-proteinase enhancer 1 antibody
    • Procollagen COOH-terminal proteinase enhancer 1 antibody
    • procollagen, type 1, COOH-terminal proteinase enhancer antibody
    • Type 1 procollagen C-proteinase enhancer protein antibody
    • Type I procollagen COOH-terminal proteinase enhancer antibody
    see all

Anti-PCOLCE antibody - Carboxyterminal end images

  • Anti-PCOLCE antibody - Carboxyterminal end (ab39204) at 1/1000 dilution + cell lysate from human neonatal dermal fibroblasts

    Performed under reducing conditions.

    Predicted band size : 48 kDa
    Observed band size : 53 kDa (why is the actual band size different from the predicted?)

References for Anti-PCOLCE antibody - Carboxyterminal end (ab39204)

This product has been referenced in:
  • Ghosh Z  et al. Dissecting the oncogenic and tumorigenic potential of differentiated human induced pluripotent stem cells and human embryonic stem cells. Cancer Res 71:5030-9 (2011). Human . Read more (PubMed: 21646469) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"