Overview

  • Product nameAnti-PCPTP1 antibody
    See all PCPTP1 primary antibodies
  • Description
    Chicken polyclonal to PCPTP1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide: MNFVDPKEID IPRHGTKNRY KTILPNPLSR VCLRPKNVTD SLSTYINANY IRGY, corresponding to N terminal amino acids 157-210 of PCPTP1

Properties

Applications

Our Abpromise guarantee covers the use of ab37240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 47 kDa.

Target

  • FunctionSequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
  • Tissue specificityExpressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localizationCell membrane and Cytoplasm > perinuclear region. Locates to the perinuclear areas within the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Ch-1PTPase antibody
    • Ch1 PTPase antibody
    • DKFZp781C1038 antibody
    • EC PTP antibody
    • ECPTP antibody
    • FLJ34328 antibody
    • MGC131968 antibody
    • MGC148170 antibody
    • NC PTPCOM1 antibody
    • NC-PTPCOM1 antibody
    • Protein tyrosine phosphatase Cr1PTPase precursor antibody
    • Protein tyrosine phosphatase NC PTPCOM1 antibody
    • Protein tyrosine phosphatase PCPTP1 antibody
    • Protein tyrosine phosphatase receptor type R antibody
    • Protein-tyrosine phosphatase PCPTP1 antibody
    • PTP SL antibody
    • PTPBR7 antibody
    • PTPRQ antibody
    • PTPRR antibody
    • PTPRR_HUMAN antibody
    • PTPSL antibody
    • R-PTP-R antibody
    • Receptor type tyrosine protein phosphatase R antibody
    • Receptor-type tyrosine-protein phosphatase R antibody
    see all

Anti-PCPTP1 antibody images

  • Anti-PCPTP1 antibody (ab37240) at 1/2000 dilution + E coli-derived fusion protein

    Secondary
    Goat anti-IgY-HRP at 1/1000 dilution

    Predicted band size : 47 kDa

References for Anti-PCPTP1 antibody (ab37240)

ab37240 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"