Anti-PC7 antibody (ab168593)
Key features and details
- Mouse polyclonal to PC7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PC7 antibody -
Description
Mouse polyclonal to PC7 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Chimpanzee -
Immunogen
Recombinant fragment corresponding to Human PC7 aa 1-591. (AAH06357.1)
Sequence:MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTG GPSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQ PAGHRPALEVEAIRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVHFNDPKY PQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPN YSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVA YGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGP HQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVT IGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTE GHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAEWV TNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIP QSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPS GMMSLIGAPRSMDSWLCVECSRHQGQTKAVRECHEWKIPAR
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Positive control
- Recombinant Human PC7 protein (ab132452) can be used as a positive control in WB. Lysate from 293T cells transfected with PC7.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab168593 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. |
Target
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Function
Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif. -
Tissue specificity
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. -
Sequence similarities
Belongs to the peptidase S8 family.
Contains 1 homo B/P domain. -
Post-translational
modificationsCysteine residues in the cytoplasmic tail are probably palmitoylated.
N-glycosylated. -
Cellular localization
Golgi apparatus > trans-Golgi network membrane. Seems to be localized intracellularly to the trans Golgi network. - Information by UniProt
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Database links
- Entrez Gene: 9159 Human
- Entrez Gene: 18554 Mouse
- Omim: 604872 Human
- SwissProt: Q16549 Human
- SwissProt: Q61139 Mouse
- Unigene: 648612 Human
- Unigene: 283283 Mouse
- Unigene: 3255 Mouse
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Alternative names
- hPC8 antibody
- LPC antibody
- Lymphoma proprotein convertase antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab168593 has not yet been referenced specifically in any publications.