Overview

  • Product name
  • Description
    Mouse polyclonal to PCSK7
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Chimpanzee
  • Immunogen

    Recombinant full length protein fragment, corresponding to amino acids 1-564 of Human DYX1C1 (AAH06357.1)

  • Positive control
    • Lysate from 293T cells transfected with PCSK7.

Properties

Applications

Our Abpromise guarantee covers the use of ab168593 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa.

Target

  • Function
    Likely to represent a ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif.
  • Tissue specificity
    Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte.
  • Sequence similarities
    Belongs to the peptidase S8 family.
    Contains 1 homo B/P domain.
  • Post-translational
    modifications
    Cysteine residues in the cytoplasmic tail are probably palmitoylated.
    N-glycosylated.
  • Cellular localization
    Golgi apparatus > trans-Golgi network membrane. Seems to be localized intracellularly to the trans Golgi network.
  • Information by UniProt
  • Database links
  • Alternative names
    • hPC8 antibody
    • LPC antibody
    • Lymphoma proprotein convertase antibody
    • PC7 antibody
    • PC8 antibody
    • Pcsk7 antibody
    • PCSK7_HUMAN antibody
    • Prohormone convertase 7 antibody
    • Prohormone convertase 8 antibody
    • Proprotein convertase 7 antibody
    • Proprotein convertase 8 antibody
    • Proprotein convertase PC7 antibody
    • Proprotein convertase subtilisin/kexin type 7 antibody
    • SPC7 antibody
    • Subtilisin/kexin-like protease PC7 antibody
    see all

Images

  • All lanes : Anti-PCSK7 antibody (ab168593) at 1 µg/ml

    Lane 1 : PCSK7-transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Developed using the ECL technique.

    Predicted band size: 64 kDa

References

ab168593 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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