Anti-PCYT1A antibody [EPR3941] (ab92440)

Overview

• Product nameAnti-PCYT1A antibody [EPR3941]
  See all PCYT1A primary antibodies
• Description
  Rabbit monoclonal [EPR3941] to PCYT1A
• Tested applicationsSuitable for: WB, IP, Flow Cyt, ICC/IFmore details
  Unsuitable for: IHC-P
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide corresponding to residues in Human PCYT1A (UniProt ID: P49585).

• Positive control
  • A549, K562, HeLa and HepG2 cell lysates; HeLa cells
• General notes

  This product is a recombinant rabbit monoclonal antibody.

  Produced using Abcam’s RabMAb^® technology. RabMAb^® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

  Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• PurityTissue culture supernatant
• ClonalityMonoclonal
• Clone numberEPR3941
• IsotypeIgG
• Research areas
  • Neuroscience
  • Neurology process
  • Growth and Development
  • Neurotrophins

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Positive Controls
  • HepG2 cytoplasmic extract lysate (ab14659)
  • K562 membrane extract lysate (ab29308)
  • HeLa membrane extract lysate (ab29547)

Applications

Target

• FunctionControls phosphatidylcholine synthesis.
• PathwayPhospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.
• Sequence similaritiesBelongs to the cytidylyltransferase family.
• Post-translational
  modificationsThe serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation.
• Cellular localizationCytoplasm > cytosol. Membrane. It can interconvert between an inactive cytosolic form and an active membrane-bound form.

• Target information above from: UniProt accession P49585 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 5130 Human
  • Omim: 123695 Human
  • SwissProt: P49585 Human
  • Unigene: 135997 Human
• Alternative names
  • CCT A antibody
  • CCT alpha antibody
  • CCT-alpha antibody

  • Choline phosphate cytidylyltransferase A antibody
  • Choline-phosphate cytidylyltransferase A antibody
  • CT A antibody
  • CT antibody
  • CTP:phosphocholine cytidylyltransferase A antibody
  • CTPCT antibody
  • PCY1A_HUMAN antibody
  • PCYT1 antibody
  • Pcyt1a antibody
  • Phosphate cytidylyltransferase 1 choline alpha antibody
  • Phosphate cytidylyltransferase 1 choline alpha isoform antibody
  • Phosphorylcholine transferase A antibody

  see all