Overview

  • Product nameAnti-PD-L2 antibody [TY25] (Phycoerythrin)
    See all PD-L2 primary antibodies
  • Description
    Rat monoclonal [TY25] to PD-L2 (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue, cells or virus corresponding to Mouse PD-L2. Mouse PD-L2 transfected cell line.
    Database link: Q9BQ51

  • Positive control
    • Mouse splenocyte suspensions and PD-L2 transfected cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberTY25
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab93589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.06-0.5µg for 105-8 cells.

Target

  • FunctionInvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
  • Tissue specificityHighly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationSecreted; Cell membrane and Endomembrane system.
  • Information by UniProt
  • Database links
  • Alternative names
    • B7 dendritic cell molecule antibody
    • B7-DC antibody
    • B7DC antibody
    • bA574F11.2 antibody
    • Btdc antibody
    • Butyrophilin B7 DC antibody
    • Butyrophilin B7-DC antibody
    • Butyrophilin B7DC antibody
    • CD 273 antibody
    • CD273 antibody
    • CD273 antigen antibody
    • MGC142238 antibody
    • MGC142240 antibody
    • PD 1 ligand 2 antibody
    • PD L2 antibody
    • PD-1 ligand 2 antibody
    • PD-L2 antibody
    • PD1 ligand 2 antibody
    • PD1L2_HUMAN antibody
    • PDCD 1 ligand 2 antibody
    • PDCD1 ligand 2 antibody
    • PDCD1L2 antibody
    • Pdcd1lg2 antibody
    • PDL 2 antibody
    • PDL2 antibody
    • Programmed cell death 1 ligand 2 antibody
    • Programmed death ligand 2 antibody
    see all

Anti-PD-L2 antibody [TY25] (Phycoerythrin) images

  • Staining of non-transfected (left) and mouse PD-L2 transfected (right) cells with 0.25µg PE Rat IgG2a isotype control (open histogram) or 0.06µg ab93589 (colored histogram). Total viable cells were used for analysis.

References for Anti-PD-L2 antibody [TY25] (Phycoerythrin) (ab93589)

This product has been referenced in:
  • Tanaka K  et al. PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol 179:5204-10 (2007). Read more (PubMed: 17911605) »
  • Kanai T  et al. Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J Immunol 171:4156-63 (2003). Read more (PubMed: 14530338) »

See all 4 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab93589.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"