Anti-PD1 antibody (ab92484)

Overview

  • Product nameAnti-PD1 antibody
    See all PD1 primary antibodies
  • Description
    Rabbit polyclonal to PD1
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A 16 amino acid synthetic peptide from the central region of Human PD1, conjugated to KLH.

  • Positive control
    • Small intestine tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab92484 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notesIHC-P: Use at a concentration of 10 µg/ml.
    WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPossible cell death inducer, in association with other factors.
    • Involvement in diseaseGenetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
    • Sequence similaritiesContains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Developmental stageInduced at programmed cell death.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD279 antibody
      • CD279 antigen antibody
      • hPD 1 antibody
      • hPD l antibody
      • hPD-1 antibody
      • hSLE1 antibody
      • PD 1 antibody
      • PD-1 antibody
      • PD1 antibody
      • PDCD 1 antibody
      • PDCD1 antibody
      • PDCD1_HUMAN antibody
      • Programmed cell death 1 antibody
      • Programmed cell death protein 1 antibody
      • Protein PD 1 antibody
      • Protein PD-1 antibody
      • SLEB2 antibody
      • Systemic lupus erythematosus susceptibility 2 antibody
      see all

    Anti-PD1 antibody images

    • ab92484, at 10 µg/ml, staining PD1 in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.

    References for Anti-PD1 antibody (ab92484)

    ab92484 has not yet been referenced specifically in any publications.

    Product Wall

    Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample Mouse Tissue sections (Pancreas)
    Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Tris-EDTA Buffer (pH 9.00)/ Sodium Citrate Buffer (pH6.00)/ Dako antigen retrieval solution
    Permeabilization Yes - Triton X-100 0.1% in PBS, Room Temperature, 15 min
    Specification Pancreas
    Blocking step 5% Serum+1% BSA in PBS as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Fixative Bouin's solution
    Username

    Francisco Rausell-Palamos

    Verified customer

    Submitted May 07 2015

    Thank you for contacting Abcam.

    I have had the chance to speak with the lab regarding your request. Unfortunately further information about the immunogens for these products is considered proprietary and can not be shared.

    I am so...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"