Anti-PD1 antibody [RMP1-30] (FITC) (ab93579)

Overview

  • Product nameAnti-PD1 antibody [RMP1-30] (FITC)
    See all PD1 primary antibodies
  • Description
    Rat monoclonal [RMP1-30] to PD1 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse PD1 transfected BHK cells 2

  • Positive control
    • 3-day ConA activated BALB/c splenocytes
  • General notes


    ab93579 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants.

Properties

Applications

Our Abpromise guarantee covers the use of ab93579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5µg for 105-8 cells.

Use 0.5µg for 105-8 cells in 100µl.





ab136125-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • FunctionPossible cell death inducer, in association with other factors.
  • Involvement in diseaseGenetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
  • Sequence similaritiesContains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Developmental stageInduced at programmed cell death.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD279 antibody
    • CD279 antigen antibody
    • hPD 1 antibody
    • hPD l antibody
    • hPD-1 antibody
    • hSLE1 antibody
    • PD 1 antibody
    • PD-1 antibody
    • PD1 antibody
    • PDCD 1 antibody
    • PDCD1 antibody
    • PDCD1_HUMAN antibody
    • Programmed cell death 1 antibody
    • Programmed cell death protein 1 antibody
    • Protein PD 1 antibody
    • Protein PD-1 antibody
    • SLEB2 antibody
    • Systemic lupus erythematosus susceptibility 2 antibody
    see all

Anti-PD1 antibody [RMP1-30] (FITC) images

  • Staining of 3-day unstimulated (left) and 3-day ConA activated (right) BALB/c splenocytes with 0.25 µg of FITC Rat IgG2b isotype control (open histogram), or 0.25 µg of ab93579 (colored histogram). Total viable cells were used for analysis.

References for Anti-PD1 antibody [RMP1-30] (FITC) (ab93579)

ab93579 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"