Overview

  • Product nameAnti-PDCD6 antibody
    See all PDCD6 primary antibodies
  • Description
    Mouse monoclonal to PDCD6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: ITDWQNVFRT YDRDNSGMID KNELKQALSG FGYRLSDQFH DILIRKFDRQ GRGQIAFDDF IQGCIVLQRL TDIFRRYDTD QDGWIQVSYE QYLSMVFSIV , corresponding to amino acids 92-191 of Human PDCD6

Properties

Applications

Our Abpromise guarantee covers the use of ab56933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCalcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)-regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis; the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
    • Sequence similaritiesContains 5 EF-hand domains.
    • Cellular localizationNucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules.
    • Information by UniProt
    • Database links
    • Alternative names
      • AIP1 antibody
      • ALG 2 antibody
      • ALG-2-interacting protein 1 antibody
      • ALG2 antibody
      • ALIX antibody
      • Apoptosis linked gene 2 antibody
      • Apoptosis linked gene 2 protein antibody
      • Apoptosis-linked gene 2 protein antibody
      • FLJ42309 antibody
      • FLJ46208 antibody
      • Hp95 antibody
      • KIAA1375 antibody
      • MA 3 antibody
      • MA3 antibody
      • MGC111017 antibody
      • MGC119050 antibody
      • MGC9123 antibody
      • PDCD 6 antibody
      • Pdcd6 antibody
      • PDCD6_HUMAN antibody
      • PEF 1B antibody
      • PEF1B antibody
      • Probable calcium binding protein ALG 2 antibody
      • Probable calcium binding protein ALG2 antibody
      • Probable calcium-binding protein ALG-2 antibody
      • Programmed cell death 6 antibody
      • Programmed cell death 6-interacting protein antibody
      • Programmed cell death protein 6 antibody
      • PS 2 antibody
      • PS2 antibody
      see all

    Anti-PDCD6 antibody images



    • Predicted band size : 22 kDa
      PDCD6 antibody (ab56933) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-PDCD6 antibody (ab56933)

    ab56933 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab56933.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"