Overview

  • Product name
  • Description
    Goat polyclonal to PDE1A
  • Specificity
    ab99476 is expected to recognize isoform 1 (NP_005010.2) only.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide:

    C-DLHKNSEDLVNAE

    , corresponding to C terminal amino acids 525-537 of Human PDE1A (NP_005010.2).

  • Positive control
    • Human Brain (Cerebellum) lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab99476 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab99476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 62 kDa).

Target

  • Function
    Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
  • Tissue specificity
    Several tissues, including brain, kidney, testes and heart.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3' 5' cyclic nucleotide phosphodiesterase antibody
    • 5''-cyclic nucleotide phosphodiesterase 1A antibody
    • 61 kDa Cam PDE antibody
    • 61 kDa Cam-PDE antibody
    • Calcium/calmodulin dependent 3' 5' cyclic nucleotide phosphodiesterase 1A antibody
    • Calcium/Calmodulin stimulated cyclic nucleotide phosphodiesterase antibody
    • Calcium/calmodulin-dependent 3'' antibody
    • Calmodulin-dependent Phosphodiesterase antibody
    • Cam PDE 1A antibody
    • Cam-PDE 1A antibody
    • CAM-PDE-1A antibody
    • HCAM 1 antibody
    • hCam-1 antibody
    • HCAM1 antibody
    • HSPDE1A antibody
    • MGC26303 antibody
    • PDE 1A antibody
    • PDE1A antibody
    • PDE1A_HUMAN antibody
    • Phosphodiesterase 1A antibody
    • Phosphodiesterase 1A calmodulin dependent antibody
    see all

Images

  • Anti-PDE1A antibody (ab99476) at 1 µg/ml + Human Brain (Cerebellum) lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa

References

ab99476 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab99476.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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