Overview

  • Product nameAnti-PDE1B antibody
    See all PDE1B primary antibodies
  • Description
    Rabbit polyclonal to PDE1B
  • SpecificityThe antibody does not cross-react with PDE1A or PDE1C or any other known PDEs.
  • Tested applicationsSuitable for: WB, IP, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptides (N terminal).

  • Positive control
    • Rat testis.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab14600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500. Predicted molecular weight: 65 kDa. This antibody labels multiple bands in the 65-72 kDa range all believed to be various PDE1B variants expressed in various rat tissues.
IP 1/200.
ICC Use at an assay dependent dilution.

Target

  • FunctionCyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
  • Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5''-cyclic nucleotide phosphodiesterase 1B antibody
    • 63 kDa Cam PDE antibody
    • 63 kDa Cam-PDE antibody
    • Calcium/calmodulin dependent 3' 5' cyclic nucleotide Phosphodiesterase 1B antibody
    • Calcium/calmodulin stimulated cyclic nucleotide phosphodiesterase antibody
    • Calcium/calmodulin-dependent 3'' antibody
    • Calmodulin stimulated phosphodiesterase PDE1B1 antibody
    • Cam PDE 1B antibody
    • Cam PDE1B antibody
    • Cam-PDE 1B antibody
    • PDE 1B antibody
    • PDE1B antibody
    • PDE1B_HUMAN antibody
    • PDE1B1 antibody
    • PDES 1B antibody
    • PDES1B antibody
    • Phosphodiesterase 1B antibody
    • Phosphodiesterase 1B calmodulin dependent antibody
    • Presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B antibody
    see all

References for Anti-PDE1B antibody (ab14600)

This product has been referenced in:
  • Oliva AA  et al. Phosphodiesterase isoform-specific expression induced by traumatic brain injury. J Neurochem 123:1019-29 (2012). Read more (PubMed: 23057870) »
  • Giachini FR  et al. Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1. Hypertension 57:655-63 (2011). WB ; Rat . Read more (PubMed: 21282562) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"