Overview

  • Product name
  • Description
    Mouse monoclonal to PDE2A
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: REKAYIPELQ ISFMEHIAMP IYKLLQDLFP KAAELYERVA SNREHWTKVS HKFTIRGLPS NNSLDFLDEE YEVPDLDGTR APINGCCSLD A, corresponding to amino acids 850-941 of Human PDE2A

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab55555 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
    • Tissue specificity
      Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
    • Sequence similarities
      Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
      Contains 2 GAF domains.
    • Domain
      GAF 1 functions as a dimerization domain, whereas GAF 2 binds cGMP, which causes activation of the catalytic activity of the enzyme.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 5''-cyclic phosphodiesterase antibody
      • cGMP dependent 3'5' cyclic phosphodiesterase antibody
      • cGMP stimulated phosphodiesterase 1 antibody
      • cGMP stimulated phosphodiesterase 4 antibody
      • cGMP-dependent 3'' antibody
      • cGMP-stimulated phosphodiesterase 2 antibody
      • CGS PDE antibody
      • CGS-PDE antibody
      • cGSPDE antibody
      • Cyclic GMP stimulated phosphodiesterase antibody
      • Cyclic GMP-stimulated phosphodiesterase antibody
      • Human cGMP stimulated 3'5' cyclic nucleotide phosphodiesterase antibody
      • PDE 2A antibody
      • PDE 2A1 antibody
      • PDE 2A4 antibody
      • PDE2A antibody
      • PDE2A_HUMAN antibody
      • PDE2A1 antibody
      • PDE2A4 antibody
      • phosphodiesterase 2A antibody
      • Phosphodiesterase 2A cGMP stimulated antibody
      see all

    Anti-PDE2A antibody images



    • Predicted band size : 106 kDa
      PDE2A antibody (ab55555) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.

    References for Anti-PDE2A antibody (ab55555)

    ab55555 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab55555.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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